The Astronomical Roentgen Telescope X-ray Concentrator (ART-XC) instrument onboard the Spectrum Röntgen Gamma (SRG) mission has started the all-sky hard X-ray survey since 2019/12/08. The observations of the ecliptic pole regions will reach exceptional depth thanks to the survey design of overlapping exposure in these regions. In anticipation of the ART-XC survey in the North Ecliptic Pole (NEP) region, we explore publicly available multiwavelength catalogs in the NEP region and investigate AGN candidates that might exhibit hard X-ray signals that will be detected by ART-XC. To capitalize on the ART-XC coverage in the NEP region, we also investigate ART-XC cadence and sensitivity limits for a selected few luminous X-ray sources. Comparisons between our simulations and the ART-XC survey in NEP will also be discussed.